In a groundbreaking collaboration between the National Dental Centre Singapore (NDCS) and the local oral care brand Pearlie White, a revolutionary antiseptic mouth rinse was unveiled on November 23. With its anti-viral properties, this everyday mouth rinse aims to play a pivotal role in reducing the transmission of viruses, including the notorious Covid-19, especially in pandemic scenarios.

The Development of a Game-Changing Mouth Rinse

The brainchild of this innovative product is Associate Professor Jaya Seneviratne, the principal investigator at the National Dental Research Institute Singapore (NDRIS). The Pearlie White Defenze Antiseptic Fluoride Mouthrinse was introduced at the Joint 37th International Association of Dental Researchers, South-east Asia Annual Scientific Meeting, and 2nd International Oral Health Symposium.

The primary mechanism of action is the suppression of the viral load in the mouth, significantly diminishing the risk of virus transmission through saliva. However, it is essential to note that other means of transmission, such as respiratory secretions from the nose, still pose potential risks.

A Trailblazing Clinical Trial: Paving the Way for Innovation

The inception of this groundbreaking product traces back to 2020 when Professor Seneviratne conducted a first-of-its-kind randomized clinical trial. Inspired by his volunteer work at a migrant workers’ dormitory, the trial specifically studied the efficacy of mouth rinses in reducing salivary Covid-19 virus (SARS CoV-2). The trial yielded promising results, demonstrating that commercial mouth rinses containing cetylpyridinium chloride (CPC) effectively suppressed salivary SARS CoV-2 levels within just five minutes of use. Remarkably, this effect endured for up to six hours post-use.

Combining Health Benefits: More Than Just Antiviral Protection

The Pearlie White Defenze Antiseptic Fluoride Mouthrinse is not just limited to its antiviral properties. It blends a potent combination of ingredients designed to combat tooth decay and bad breath. This unique formulation positions the mouth rinse as a versatile daily-use product, addressing multiple oral health concerns simultaneously.

Strategic Implications for Healthcare Settings

Marco A. Peres, NDCS’ deputy chief executive officer for research and education, highlighted the potential of this mouth rinse in managing the spread of aerosol-transmitted viruses. Beyond protecting the general public, the mouth rinse is expected to significantly reduce cross-infection between patients and healthcare workers. In clinical settings involving aerosol-generating procedures, such as intubation for general anesthesia, this innovation becomes especially crucial. Professor Peres emphasized the added layer of protection it provides to dentists and dental providers during procedures that generate aerosols.

Translational Research: A Collaborative Triumph

Singapore’s chief dental officer, Chng Chai Kiat, praised the collaboration between NDCS and Pearlie White, emphasizing the synergy that harnessed the best expertise from both sides. The translational research behind the mouth rinse stands as an exemplary collaboration, merging oral health research expertise with industry knowledge. This collaboration resulted in a unique mouth rinse with the potential to benefit the wider public.

Features and Accessibility

The Pearlie White Defenze Antiseptic Fluoride Mouthrinse boasts several user-friendly features. It is alcohol-free, halal-certified, and proudly made in Singapore. Moreover, the mouth rinse incorporates ingredients dedicated to combating bad breath and tooth decay. These additional features contribute to its appeal and usability for a broad spectrum of users.

Affordability and Availability

For those interested in this groundbreaking product, a 750ml bottle of the Pearlie White Defenze Antiseptic Fluoride Mouthrinse is priced at $14.90, making it an accessible option for those seeking enhanced oral health and antiviral protection.

In conclusion, the launch of this antiseptic mouth rinse marks a significant advancement in the field of oral care, particularly in the context of pandemic preparedness. As it combines antiviral efficacy with everyday oral health benefits, it exemplifies a holistic approach to maintaining oral hygiene in the face of evolving health challenges.